Slime is a liquid dropped in large amounts in a 3x3 area after killing Giant Amoebas. It can also be produced by anyone with the Slime Glands mutation. Anyone attempting to cross tiles covered in the stuff has a chance to slip in the direction opposite their approach. Drinking it inflicts the Confusion status effect on the drinker. It is also used as a cooking ingredient, in which case it gives meals slime-spitting effects.

It can be turned into Gel using a Desalination Pellet, which has a number of medical uses.