This book can always be found for sale by the mayor of Kyakukya, who can be found in his house in the middle of town. The book contains descriptions of long term status ailements that have debilitating effects, and their cures. Most notably, it contains the cures for Glotrot, Ironshank and Glowcrust. While the descriptions of diseases remain consistant between playthroughs, the recipes for the cures are randomly generated each new game, making the images posted below almost useless for metagaming.
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